Yes. Meaningless. 1492? Very meaningful.

One of the most important feats if not the most important of what we used to call the Age of Exploration: https://en.wikipedia.org/wiki/Age_of_Discovery

This led to global trade that changed the face of the earth. It opened philosophical debates about human rights, the legality of wars, etc., which are still important today.

https://plato.stanford.edu/entries/school-salamanca/#IusGent...

These debates led to the prohibition of American Indian slavery in... 1542!

https://en.wikipedia.org/wiki/New_Laws

The first recorded christian marriage in current United States was an interracial union in 1565!

https://en.wikipedia.org/wiki/Slavery_in_colonial_Spanish_Am...

I could go on an on.