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Principally by making lots of interesting submissions. From http://searchyc.com/user/nickb :

941 comments, 2.97 points per comment

3514 submissions, 6.00 points per submission

But how do you make 3514 submissions + 941 comments. That is as if you spend 8 hours a day on YC.

I think he automated a script to do interesting submissions and amazing comments ;)

And does his employer know? ;)