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You can persist data on the client with IndexedDB and make a SPA with zero load times no matter what page you’re loading. That would never be possible with a MPA. It’s also almost never something that actually happens with SPAs but it certainly is possible.

The best example I know of a purely client-side web app that makes effective use of local storage is the Pinafore [1] client for Mastodon.

Edit: And it's worth noting that this app is a labor of love by an expert web developer, i.e. the antithesis of a typical corporate project.

[1]: https://pinafore.social/

Playing audio or video without interruption while navigating the site.

Somewhat niche but a good use case, thanks.

Eh unfortunately its muddy there too, see changelog.com which is not an SPA and instead uses Turbolinks (now Turbo) to persist the podcast element at the bottom of the screen.

Spreadsheet apps in the browser?