This depends almost entirely on the accuracy of the simulated environment relative to the real world. If we have very accurate simulators then sim2real isn't too bad. If we have poor simulators (or simulators which don't fully capture that <0.1% probability action that happens to have REALLY bad consequences...) then sim2real doesn't work.
Flying a drone through a static forrest in no-wind (no moving branches, etc.) seems like a reasonable sim2real environment, in part because... well... video games have had forrests and trees don't tend to move very fast unless there's wind.
But sim2real for self driving cars is a lot harder given the huge diversity in streets and freak events that happen (people, bicycles, shopping carts, piano-delivery-trucks)
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