That’s not my kind of thing, nor do I have the experience, but at that price, wouldn’t you be better off using a Raspberry Pi (or similar) to control the fans, place thermometers, etc?
I understand that having a computer inside a computer is silly, but we are kind of in that rabbit hole anyway. And a GPIO would be more reassuring to me than depending on driver support for one motherboard/usb fan controller.
Just random thoughts