There are a lot of infamous incidents caused by people thinking they know better than the people who designed stuff and actually had training, experience, and education in that field. Doing things like changing fastener grades, or styles, or completely changing how something is put together. The most ready example I can think of is the hotel bridge collapse that killed a couple dozen people, because some mouth-breather thought he knew better than the structural engineers that drew up plans on how to anchor the bridge to its overhead supports.
Virtually nobody at a hospital is qualified to second-guess vaccines, and the people who do are people I don't want anywhere near patient care because they're going to second-guess other experts, like the doctors they work with, the instructions for equipment and drugs, etc.