Wolf tones are certain notes which don't sound very well which vary between instruments due to their construction. I think you mean the Pythagorean comma.
Pythagorean comma is the difference between enharmonic notes in Pythagorean tuning, e.g., difference between Ab and G#. Not what I was talking about.
With any 12-tone system, you might have eleven fifths which are 700-x cents wide, on average... and then a diminished sixth (rather than a fifth), which is necessarily 700+11x cents wide as a result. The "wolf interval" is the diminished sixth (commonly G# to Eb, or C# to Ab). In equal temperament, the diminished sixth is equal to a fifth. You might also call something other than a fifth a wolf interval. Basically, an interval which normally sounds good, except you chose an enharmonic version of it, which sounds bad.
"The" wolf interval is the quarter-comma meantone diminished sixth, which is 2^7 / 5^(11/4) = 1.5312. The Pythagorean wolf interval is 2^7 / (3/2)^11 = 1.4798. It's equal to a perfect fifth, minus the Pythagorean comma.
https://en.wikipedia.org/wiki/Meantone_organs_in_North_Ameri...
It was Werckmeister who popularized and advocated systems which don't have wolf intervals (so-called "well temperament", as in "Bach's well-tempered clavier". The composers who cared about wolf intervals generally predate Bach, to give you an idea.
Nowadays (since the 1980s) I can press a button and put my synthesizer or electronic piano in whatever tuning I want, so I can play with quarter-comma meantone temperament without finding one of the organs on the list, and experience it myself.