Hormone links exercise with cognitive benefits
nia.nih.gov
nia.nih.gov
see also
https://pubmed.ncbi.nlm.nih.gov/25952527/
"Irisin, as a new hormone-like myokine, is discovered in the presence of exercise-induced peroxisome proliferator-activated receptor gamma coactivator-1-alpha (PGC-1α)."
That sentence is not giving me much hope that they expect the hormone to survive digestion.
"In addition, the researchers found that irisin could cross the blood-brain barrier to act on the brain."
Anyway, there was a ton of research done that people over 60 can still put on muscle mass. Which obviously protects from injuries, supports posture, etc.
We also have studies showing that long term runners don't have a higher incidence of knee problems than non-runners, so it does seem that the cartilage damage DURING exercise is compensated by said exercise, assuming correct form and all that.
If you're lucky, you'll feel it couple of days before. Than you can rest, say goodbye and die in your sleep.