80-90 years of mobility or 85-95 years trapped in one place is not a hard choice to make, especially when 60+ of those years are still in the future.

Yes, the pollution from cars is terrible. I lived by a major freeway for three years. No, the solution is not to give up all their benefits. For one thing, SF could actually enforce air quality standards inside apartment buildings, especially those near the freeways. Also future storm drain systems could be designed to settle out microplastics (many storm systems do have settling/collection ponds anyway).