Certainly no-one would make the claim that "there are (definitely) no aliens in the galaxy" when we can't disprove the idea that aliens traveling at the speed of light just reached the galaxy (with our current understanding of physics). That doesn't mean you can't make the claim "there are (almost definitely) no aliens in the galaxy (because I just created the most amazing telescope ever and looked at every particle of matter in the galaxy and there were no aliens there)". The principle of charity demands that understand the bare claim that "there are no aliens in the galaxy" to mean something that is plausible, such as "there are almost certainly no aliens in the galaxy".