Ivermectin for Prevention and Treatment of Covid-19 Infection

From the report: "Meta-analysis of 15 trials found that ivermectin reduced risk of death compared with no ivermectin (average risk ratio 0.38, 95% confidence interval 0.19–0.73; n = 2438; I2 = 49%; moderate-certainty evidence)." There's futher meta-analysis from 64 studies on Ivermectin as a treatment and prophylaxis for COVID-19: https://ivmmeta.com/

There is much commentary in the media about Ivermectin being a "horse dewormer" when it was for human use first and then for animals. There are many, many drugs for humans which obtain FDA approval for animals. The real question here should be whether off-label use is appropriate and warranted, not whether the primary use for this drug in western countries is for quadrupeds.

I flagged this because it's a biased source, not the best review. The most authoritative review currently is this one from Cochrane: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD...

And some interesting more recent commentary that helps put it in perspective: https://www.cochrane.org/news/ivermectin-cochranes-most-talk...