Unlikely. Safari supports stateless filtering (ie the blocker app doesn’t get to see your traffic, but just submits rules), and Gorhill has said uBlock cannot work with this restriction[0]. I understand Apple’s wanting to keeping blocking apps from spying and to ensure performance of the blockers, but the lack of uBlock on iOS is a huge pain point for me.

[0] https://github.com/el1t/uBlock-Safari/issues/158

Content blocking has been possible for a long time.

I don't know much about ublock, but I've got a Safari content-blocker set up that pulls from a custom set of easylist files and blocks all requests to those URLs from within safari

Try 1Blocker.

https://1blocker.com/