In my nearly 40 years of being alive, I've personally encountered 3 broad "categories" of people so far:
1. Religious types, who are super uncomfortable with the unknown and wave it away by pointing to "God".
2. Scientism adherents, who are also super uncomfortable with the unknown, and wave it away with, what looks to me like, a magical belief in science ("science can't explain this, but I totally trust that it eventually will"). They like to denigrate people in category (1) without realizing they're guilty of a similar kind of magical thinking.
3. Mystics. They appreciate science and its shortcomings and don't resort to magical thinking. They're capable of non-dualistic thinking. They don't resort to "God" or "science" to wave away the unknown. They're comfortable with being uncomfortable as just yet another part of the human experience. They accept their personal limitations and make no declarations about the existence or non-existence of things about which they could not possibly know.
1, 2 and 3 also roughly model the various stages of individual development outlined by M. Scott Peck in "Further along the road less traveled" [1].
[1]: https://en.wikipedia.org/wiki/M._Scott_Peck#The_four_stages_...