Tuskegee was many decades ago. There are much more recent examples of the pharmaceutical industry and doctors prescribing a product to millions of Americans that was later shown to be harmful, at least for some patients. I'm of course referring to Oxycontin and other supposedly "non-addictive" opioids. Hundreds of thousands of Americans have died as a result of these drugs. Countless more lives stunted or ruined.
In my view, events like this explain a great deal of working-class (including white, who heavily lean Republican) skepticism about novel treatments. Just today, Pfizer issued a complete recall of the anti-smoking drug, Chantix, after discovering it can increase cancer risk:
https://www.usatoday.com/story/money/shopping/2021/09/17/cha...
I hope we all can have more empathy for anyone who is skeptical after witnessing or experiencing harm after a incident like this. I'm not saying all fear or skepticism is valid or warranted. Just that I wish people would not judge the individuals involved for their (presumed) politics, and work towards greater education and understanding.