If there is a field of science that needs a paradigm shift, it's obesity research. I can't think of any other aspect of health that has continually worsened, worldwide, for decades on end.
Psychiatric prescriptions over the same decades correlate with a large rise in the disorders they treat. Drug addiction has responded to imprisonment more than any healthcare initiatives. Not saying it's exactly analogous, just that obesity health is not so unique, and really only stands out because of its innocuous or "innocent" causes and visible ubiquity.