I've been using Nebula for personal use and it's really great. I have a free Oracle Cloud vm as my "lighthouse."

The advantage of Nebula is that it's dead simple. Generate a keypair, copy it over, copy the config file, and go. It can do mesh routing for the vpn and traverse nat magically. You can delegate dns to the lighthouse and name resolution just works too.

That simplicity is awesome for personal use, and maybe it's good enough for a small operation, but I'm guessing it doesn't have all the bells and whistles you'd want for medium or larger companies.