I assume the async story is going to be more fun.
By the way, if you are looking for a good key/value store with expiration without the need to setup redis, have a look at the excellent diskcache:
https://pypi.org/project/diskcache/
It is based on sharded sqlite files, and it's surprisingly capable, even in multiprocessing based env like a django site.
Sqlite is really showing up in all sort of use cases these days, like huey, a task queue that doesn't need any broker to be installed to be useful: https://pypi.org/project/diskcache/
Now things can get fun...
With supervisord (supervisord.org) you can manage multiple processes, and with fastapi + starlette, you can serve your WSGI site without a proxy pass, including static sites: https://fastapi.tiangolo.com/advanced/wsgi/
Then with shiv you can bunddle all that in a pyz file: shiv.readthedocs.io/
Meaning you can now just upload a pyz file to your server, run python on it, and that's it, you have a full stack deployed, with a web framework, db, caching, task queues, static file serving, which can handle around 100k visitor each day without a sweat.
No more infra needed. Just Python code, all bundle in one file.
That's really neat.