In two years, I fully expect Rust to begin taking off as a major frontend language choice. A framework like Seed will help usher this in.
It'll be faster than Javascript, eventually multithreaded, and produce portable binaries that can run on a wide variety of platforms and architectures.
It'll paint to DOM, but also do immediate mode and other types of rendering.
We'll see incredibly rich applications: games, video editors, IDEs, etc.
Electron will yield to this. We'll have fast, cross-platform apps that run not just on the browser, but natively on Windows, Linux, and Mac.
If we're lucky, we might even start writing mobile apps this way and ditch the iPhone/Android specific APIs.