Everyone who has programmed full-time for a good number of years will have had some of the negative effects, even though many go in loving programming itself. Things around programming, mostly the very things that make programming a practical skill, like making money, using frameworks and libraries, deadlines etc can make it a horrorshow. If I just work on little fun projects no one will ever see, I am that boy from 40 years ago again who loved every second of writing software.