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It's CPU specific in the sense that the CPU needs IOMMU instructions (almost everything made in the past 10 years) and OS version specific in that Windows and Linux have both supported it for about 3 years.

The problematic part is that the UEFI needs to support it, it seems most systems with Thunderbolt have enabled it since 2018 and systems without Thunderbolt still don't bother.

Most hardware features need that kind of adoption to work.

It's mandatory for thunderbolt 4.

Should I say "mitigated"? But DMA itself is a core part to improve transfer performance, and itself is a security hole.

Anyway mitigation is considered to enough TB/USB4 to be adopted for new devices.