Clinical efficacy of nitric oxide nasal spray for treatment of mild Covid-19

Sunlight exposure and exercise also stimulate nitric oxide production. This could be one of the reasons why sedentary people are 4× more likely to die of COVID-19 than active people.

https://bjsm.bmj.com/content/early/2021/07/21/bjsports-2021-...

Giving the upswing in cases (including breakthrough) something like this could be very useful in terms of reducing transmission.

> Patients in the NONS treatment arm demonstrated viral loads, as determined from PCR testing of nose and throat swab sampling, that were lower at days 2 and 4 by a factor of 16.2 than those on placebo, and symptom resolution was also found to be faster on NONS treatment than on placebo in this study.

> Accelerated SARS-CoV-2 clearance with NONS may reduce symptom duration, decrease infectivity period, reduce hospital admissions, and lower disease severity