I have a theory of signalling for mental health.
There are very few conditions that are real and they have easily detectable and unambiguous physical signs, e.g. epilepsy.
The rest of them are ways for people to show distress, either positive or negative. The positive side would be stigmata 'look at me and how holy I am' the negative would be witches 'look at me and how unholy I am.
Transgenderism moved from the negative distress to the positive distress pile in less than 5 years last decade and people are having a hell of a time dealing with it.
The 'acceptance' of deviancy isn't helping, it's just pushing people to become more extreme in what they do to show their dislike of current society.