The way I do it is to have a palette of base ingredients for each of fat, acid, and heat. You can create a lot of beautiful, artful meals with a very limited palette. My fat palette, for instance, is primarily rendered animal fats (pork lard, then beef tallow, then chicken fat, in order of frequency of use--we sautee and sear in, and even eat on toast, almost exclusively rendered animal fat). Then olive oil for finishing and occasionally cooking (e.g. some kinds of fish poached in olive oil is heavenly).
Acid palette is limes/citrus and rice vinegar.
Heat palette is certain peppers and some hot sauces.
All healthful ingredients that can be applied to endless proteins and veggie combos.
The standard American pantry of like a billion different spices and sauces and the United Nations of possible ethnic food types means invariably lots of preservatives and in general mediocre (at best) meals. No non-pro cook can crank out high-quality carne asada one day, then a penne vodka, then an injera platter.
But the answer is: Rendered animal fats are the best substitute, and the real answer is, don't eat processed bullshit food. (Aside: "Lab grown" branding is doing a great job tricking smart people into believing "highly-processed factory-made" is somehow healthy).