> Whether it be treatments or interventions, the plethora of seemingly similar quality research supporting contradictory positions, and the use of digital echo chambers, facilitates widespread confirmation bias - evidence supporting any initial position can be easily found. Self-serving bias and cognitive dissonance further make it challenging to alter positions, especially for those taking very public and strong positions with serious implications. We felt that attempts to organize and make the research and data easier to navigate, highlighting areas of applicability, and analyzing limitations, could potentially be beneficial.

> What is the search strategy for papers? All significant original contributions related to the use of the treatments we cover, including searches of the typical sources augmented by contributions from the community. Covering all research is important because it is easy to choose a search strategy that results in a subset of papers reporting a desired conclusion. This is especially so if one takes the conclusions reported in papers at face value without examining the actual data, methods, or regions of applicability