A perennial. Here are the threads with comments. They're not very large are they:

You and Your Research – Richard Hamming - https://news.ycombinator.com/item?id=27451360 - June 2021 (1 comment)

You and Your Research - https://news.ycombinator.com/item?id=25242617 - Nov 2020 (1 comment)

Richard Hamming: You and Your Research (1986) - https://news.ycombinator.com/item?id=24171820 - Aug 2020 (1 comment)

You and Your Research – A talk by Richard W. Hamming [pdf] - https://news.ycombinator.com/item?id=23558974 - June 2020 (1 comment)

You and Your Research by Richard Hamming (1995) [video] - https://news.ycombinator.com/item?id=18505884 - Nov 2018 (10 comments)

You and Your Research (1986) - https://news.ycombinator.com/item?id=18014209 - Sept 2018 (10 comments)

You and your research - https://news.ycombinator.com/item?id=14179317 - April 2017 (1 comment)

You and Your Research, by Richard Hamming - https://news.ycombinator.com/item?id=10280198 - Sept 2015 (1 comment)

You and Your Research - https://news.ycombinator.com/item?id=9279585 - March 2015 (1 comment)

Hamming, "You and Your Research" (1995) [video] - https://news.ycombinator.com/item?id=7683711 - May 2014 (25 comments)

Video of Hamming's "You and Your Research" (1995) - https://news.ycombinator.com/item?id=5567448 - April 2013 (1 comment)

Richard Hamming: You and Your Research (1986) - https://news.ycombinator.com/item?id=4626349 - Oct 2012 (27 comments)

Richard Hamming: You and Your Research - https://news.ycombinator.com/item?id=3142978 - Oct 2011 (7 comments)

You and Your Research - https://news.ycombinator.com/item?id=915515 - Nov 2009 (5 comments)

Richard Hamming - You and your research - https://news.ycombinator.com/item?id=852405 - Sept 2009 (1 comment)

You and Your Research - https://news.ycombinator.com/item?id=625857 - May 2009 (13 comments)

You and Your Research (1986) - https://news.ycombinator.com/item?id=542023 - April 2009 (4 comments)

You and Your Research - https://news.ycombinator.com/item?id=524856 - March 2009 (1 comment)

Richard Hamming: You and Your Research - https://news.ycombinator.com/item?id=229067 - June 2008 (7 comments)

Why do so few scientists make significant contributions and so many are forgotten in the long run? - "You and Your Research" - https://news.ycombinator.com/item?id=52337 - Sept 2007 (11 comments)

You and Your (Great) Research - https://news.ycombinator.com/item?id=13218 - April 2007 (6 comments)