There is however a bijection between the natural/countable numbers and every number that mathematicians, physicists, and any other scientist have every used in all of human history (or will ever use). Start with the computable numbers, and then generalize to anything that has been written down in symbolic text.
It's very hard to point to a real number which is not in the set of computable numbers, and for the few examples (Chaitin's constant(s) etc...), there are countably many of them.
From this point of view, I'm curious whether the computable numbers are sufficient to do integral and differential calculus etc... (basically all "normal" math that engineers or applied scientists might use) Maybe it requires a different definition of limits, I dunno. What number are we interested in that can't be done with computable numbers?
At what point do we need Real numbers and their mind-blowingly weird properties?