Every mouse I tried (suggested by reviews) does oops clicks sometimes, so I always turn off side buttons and live with the fact that they are just there discomforting my thumb.
I don't touch the side buttons when gripping or rebasing the mouse. That's not a G502 but every mouse I've tried so far (except for the G600) has been grippable without touching any buttons.
Also, the form factor and things like the Ploopy Nano are super cool. And because it's open source if you don't like the hardware/software you can easily change it. We use interface devices all day, everyday. Not having an ergonomic interface will catch up with you.
It's almost always used ironically, but there are probably a few edgy GamerGate types who take it to heart.