Jump 20 by AeroVironment with a wingspan of 5.7m and a payload of 13.6kg[0].

A tweet from Spanish police with a video of the compartment[1].

A Vice article about the same drone[2]. At the end it says, "Police found seven drones, each with load capacities of between four and 25kg," which puts the biggest at 1/6th the capacity of this one. Allegedly.

For perspective, the Aerolite-103, a single-seat ultralight aircraft with a maximum fuel+pilot+cargo takeoff weight of 147kg and a wingspan of 8.18m[3].

Of course, it's not like police would over hype[4] a drug bust[5].

[0] https://www.avinc.com/uas/jump-20

[1] https://twitter.com/policia/status/1414875097752653826?s=20

[2] https://www.vice.com/en/article/dyvwmv/look-at-this-huge-dru...

[3] https://en.wikipedia.org/wiki/Aero-Works_Aerolite_103

[4] https://www.buzzfeed.com/aliciabarron/people-are-totally-und...

[5] https://www.metro.us/nypd-makes-the-most-pathetic-drug-bust-...

I don't see typical commercial drones carrying major shipments but they could be used for small drops or for ISR operations to check on border crossings or overwatch during other activities.