I imagine that the same idea applies for more general languages, so, I expect the derivative of a language with respect to a character, is the language of strings such that prepending one by the character results in a string of the original language.
So, if R_1 and R_2 are two different regexes, then the derivative with respect to c of the regex R_1 | R_2 , i.e. \partial_c (R_1 | R_2) , would be (\partial_c R_1) | (\partial_c R_2),
and, if + is used for concatenation of two regexes, the derivative of R_1 + R_2 would be, ((\partial_c R_1) + R_2) | ((if R_1 accepts the empty string, then the language which accepts only the empty string, otherwise, the language that does not accept any string) + (\partial_c R_2))
etc.
... I think.