Interpolated translation is continuous and easily differentiated. There's lots of work on machine-learned video codecs already, from Nvidia, Qualcomm and others.
I've tried them, the current state of the art means that they're only useful on relatively static things (some shaking etc) while spike up to AV1-level bitrate to reach perceptual similarity when the movement is too much. Maybe in the future (or whatever under the wraps concoction Nvidia, Qualcomm or another player have), ML-based video codecs will surpass handtuned codecs, but it's not (yet) the present state.
The premise was using e2e learning to avoid patent issues. I am sure that with some preprocessing you can plug a NN inside the deciding process and learn very meaningful stuff.