The same thing leads to keyboard fanatics trying to get all typing from the fingers without moving their wrists or arms; that seems likely to be a terrible recipe for RSI.
As a user of multiple large monitors for many years, I enjoy actually turning my neck, rotating my body and moving on the chair to orientate around different parts of the screen space. Probably I have to actually re-focus my eyes as well, as the screen edges are a little further away, too.
I heard this is similar to pianists, who say you should only play from the fingers if you can't move the wrist, and from the wrist if you can't move the arm.
Am I the only person who thinks a certain level of physical interaction when at the PC is actually a good thing?