"Overall, the reliable evidence available does not support the use ivermectin for treatment or prevention of COVID‐19 outside of well‐designed randomized trials."
"Overall, the reliable evidence available does not support the use ivermectin for treatment or prevention of COVID‐19 outside of well‐designed randomized trials."
"Ivermectin showed no evidence of an effect on increasing or decreasing mortality at 28 days, the most important outcome during this pandemic, neither in inpatients (two studies), outpatients (two studies), or the preventive setting (one study). The certainty for this finding was very low. The same accounts for clinical worsening up to 28 days in an inpatient setting and up to 14 days in an outpatient setting."
Bear in mind that 'bias' with regard to ivermectin is less likely to come from doctors than it is pharma companies. Doctors stand to gain nothing from the efficacy of ivermectin since it's a generic drug on the market since 1987. Pharma companies have a lot to lose if it's proven effective.
To control for bias one ought to look at larger sample sizes. And each time that happens there's a significant result.
This is an obvious financial win to any slightly competent evil pharmaceutical - e.g., make some small chemical variant of ivermectin, patent it, and p-hack a bit. Or just manufacture the generic and sell lots of it; plenty of companies have a good business selling aspirin, which literally grows on trees.
I'm not buying the "big pharma is trying to censor it" angle. Also, like any conspiracy theory, it requires a whole lot of people to be perfectly loyal and silent. If ivermectin is actually effective, some pharma exec with family in a part of the world with poor vaccine access is going to push for it.
Also I'm mostly referencing the idea, which I believe I've seen in some of these papers, that people should take ivermectin on an ongoing basis to protect against getting infected in the first place. If I were a pharma exec who knew that ivermectin secretly worked, I wouldn't want my family to get sick at all if I could help it - I'm pretty sure no paper is claiming it's 100% effective, it just reduces the chance of poor outcomes. So I'd have to tell them to find a doctor willing to prescribe ivermectin even before they're sick, and that would definitely leak.
https://covid19criticalcare.com/guide-for-this-website/take-...
That website lists doctors who will hotline you a prescription. Maybe it's harder outside the US, but I know you can get off branded forms of it (perhaps those are worth less confident in?)
I would argue the secret isn't being kept. It just circulates in one silo and not all silos of our reality schism.
Brett Weinstein has made a lot of dubious claims so I am skeptical to what he says. He at one point has claimed that Ivermectin is 100% effective when taking prophylactically based on a single study that has received a lot of criticism for having numbers that dont make sense. To me it seems that he needs to be more critical of the sources he uses.