I never really got into it properly (though I paid for and used feedbin for a while) not least because not everything supports it. Its main attraction to me is as being the one place I can go for everything, and if it isn't that, then.. meh, it's just another thing to check, and I gradually stopped.
Not that I don't intend to go back (as much as I intend to do a lot of things..) - it just needs more setup to be useful to me, email subscriptions to RSS for example, or perhaps even the other way around, have an email folder full of subs with rss forwarded there too.
Other things that annoyed me were latex not rendering, and the RSS article being just a tiny stub, or title only, linking to the real deal.