People with a background in methods like solving problems that are easy to solve with the methods they know. Those are rarely the problems people in biology/medicine want to solve. Some common pitfalls include:
* Asking the right questions.
* Framing the questions correctly.
* Finding computational problems that capture the essence of the questions and that can be solved efficiently.
* Interpreting the results.
* Avoiding systemic biases in rare but important edge cases.
Finding the right problems to solve takes time, and the first attempts will probably fail.