"Neither primed CD4+ nor CD8+ T cells appeared critical for immunoglobulin class switching, the development of immunological memory, or protection from a second infection." this seems reasonable, it never made sense to me that one can not get reinfected. for depletion, it would seem then a counter to the second dose argument, yet again I revert back to my statement above that to me I'm positioned in that I can wait for the fog to clear a bit. A lot of this seems very early days in the Iraq war when the media and admin were in the same boat for the purpose of the invasion etc.
second dose is to boost antibody levels (tcell also rise, but their effectiveness is... ) . but over the time they go down. third dose helps to boosts it way up