I have to disagree with almost all of the points you raise.
The degree to which you wish to (re)model data is a design decision - also within a DW. This is what I mean by divorcing the tech from the practice. Methods to store and manipulate semi-structured data exist within cloud data warehouses and there is nothing inherent in the technology preventing from extending said support. Also, it seems to me, that even in advanced analytics incl. ML one eventually works with the data in a tabular form anyway.
When it comes to performance, I was referring primarily to e.g. cross-domain queries. That continues to be challenging in data virtualization / federated query engines.
You (and data mesh) focus on the domains - and nothing prevents carving out ample portions of storage and compute from a cloud DW to them and doing the exact things you propose. Except that "federated computational governance" and enforcing standards is now heaps easier since everyone is relying on the same substrate.
Data mesh targets analytical workloads - and surely you do not suggest e.g. hooking Trino up directly to operational, OLTP databases? One has to, as least how things stand today, copy the data somewhere anyway for not the least historical analysis, as well as often transform it to be understandable to a downstream (data product) consumer. So you will have "pipelines" no matter what - even in a data mesh.
Not only are the domain teams free to build the aforementioned pipelines and model data in any way they see fit - within a cloud-native DW, but also the DataOps tooling available in this area is already relatively mature.
The only part I can somewhat relate to is about "forcing" to rely on a specific piece of technology. But I think that is just something one needs to accept in a corporate setting and a balancing act. And I'm talking about the majority of the regular companies out there, not FAANG. Also, there other arguments to be made - such as avoiding vendor lock-in or if the capabilities of the DW simply does not cater to the specific problem your domain has. But these are not the arguments you made.