The promise of G100UL is that that FBO can (eventually) sell this fuel to all gasoline-fueled airplanes.
Automotive engines are overwhelmingly water-cooled [providing a far more stable and lower cylinder head temperature], variable/computer-controlled timing often with knock sensing [providing the means to adjust timing dynamically when anything beyond light pinging is detected], closed-loop fuel control, and rarely producing more than 20% of their rated power.
Aircraft engines need to stay together with a cylinder head temperature of 460ºF, fixed timing, and fuel mixtures that are set by the pilot. It's a far more demanding (and less controlled) environment.
Some additional refs that might be interesting:
https://www.avweb.com/features/pelicans-perch-43detonation-m...
https://www.avweb.com/features/pelicans-perch-55lead-in-the-...
https://www.avweb.com/features_old/pelicans-perch-31those-fi...
When I was flying a turbocharged cirrus (notoriously hot running engine) we always kept the cylinder heads to 380F. It limited our climb performance but was so much better for the engine.
Nevertheless, it’s a certification requirement that the engine have appropriate detonation margin at the manufacturer’s declared CHT redline and TCM/CMI has chosen to put their redline around 75°F higher than I’m comfortable in normal operations.
The engine can sustain 840C, it can go to 870 for less than 20 seconds and it can even sustain 1000C for up to 5 seconds without triggering any kind of exceedance.
Basically any engine made by a European engine manufacturer takes "mogas" without incident, and prefers it because lead causes issues. But to the sibling comment's point, those engines also have goodies like single lever power (so no direct mixture or rpm control). That changes the parameters a lot.
Edit: to add on, if you're in an experimental plane, you can do all sorts of things to your engine. You can buy aftermarket electronic fuel injection and ignition kits with variable timing, and reclaim a good deal of fuel economy in the process. Most engines that these kits support will then quite happily run along with a fuel like 94UL. Some people have even converted automobile fuel ignition controllers for the purpose (I hear the Ford V8 ECU is pretty popular for this).