And I'm not even talking about some newfangled APIs like WebUSB and such (I don't really care about those personally). Safari's handling of regular HTML + CSS is regularly broken compared to other browsers. (At least in my experience.)
Open the site in Chromium. Yep it works. Open the site in Firefox. Yep it works. Open the site in Safari. Ugh... it's broken.
That's something that I encounter on a regular basis.
It's really inexcusable that Apple, being the richest company in the world, has a web browser that's this bad. But they don't really have any incentive to do better. Thanks to their walled garden the only available web browser on iOS is Safari, and since no developer can afford to ignore iOS as a platform they have no choice but to deal with it.