Believing in science means believing in falsification and sceptism. This was published during the ongoing replication crisis in medicine where we're finding that more than half of cancer studies don't replicate [1]. This replication crisis hasn't been put on hold and all science is now deemed irrefutable or you are VACCINE HESISTANT and DANGEROUS.
I'm mostly confident in the COVID vaccines because we're at billions of doses and there is so much uncorrelated data about the vaccines, and they're so controversial and their safety/efficacy is being looked at by so many people that one can be relatively confident about their efficacy and safety (so long as you look at uncensored information to avoid systemic bias). We don't need to be science denialists and start denouncing scepticism on safety grounds, we can point out there are special reasons to be confident in the vaccines.
[1] https://www.npr.org/sections/health-shots/2017/01/18/5103048...