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elromulous

dang - can we add "in mice" to the title?

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Yup, always up for that. almost tempted to write some code to try automating it

Haha first proper laugh of the day

Every study works in mice.

Human trials, not so much. Also, who would volunteer for depression + psychedelics before and after brain biopsies to prove this thesis? Maybe try it on the "before" sample in vitro first?

This seems like something that could be measured with at least one of the scanning techniques we already employ. It seems like an MRI could provide a rough result that could lead to further and more direct testing.

Gross structural scanning is essentially worthless when it comes to pathway functions.

Of course it doesn't. The fact that we don't hear about all the trials that don't produce a significant result in mice is more to do with the state of science publication than to do with mice.

I'm always impressed how quickly you respond to the bat-signal.

It's a sample-bias illusion, like the Super Bowl prediction scam.

Could you explain a bit more? Or point to a ressource / story? (Failed to find something relevant by searching!)

There's a classic scam where you send a letter correctly predicting the Super Bowl winner and then collect "investments" for your future predictions (i.e. scam people out of their money). The trick is just to mail out the same letter for every team.

I guess it's hard to google because anything involving "super bowl" is quite a haystack. But apparently it's called the "Perfect Prediction Scam": https://www.google.com/search?q=%22perfect+prediction+scam%2....

Apparently Alfred Hitchcock did a TV episode about it: "The Mail Order Prophet" (1957):

http://barebonesez.blogspot.com/2016/02/the-hitchcock-projec...

https://www.dailymotion.com/video/x6uue06

"I wish he hadn't done it. We have a very sensitive elevator man. He doesn't like it when he brings people up, and then they don't ride down again. It confuses him."

Given that he just expressed his affinity for writing code for things, I'd assume the bat-signal also sounds a buzzer in the HN-cave... ;)

i forgot what thread was that, but someone linked this twitter account lol

https://twitter.com/justsaysinmice/status/141214323096402739...

What we need is some code to turn a human to a mouse.

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