Elevated levels of autophagy after fasting result in the elimination of senescence-like neurons. Individual neurons of this type can negatively influence the extracellular environment and may promote induction of the same phenotype in surrounding cells, as well as driving aging and age-related diseases.
https://link.springer.com/article/10.1007/s12603-013-0344-9
https://www.sciencedirect.com/science/article/pii/S027858462...
I experienced none of the effects. People claim to be sharper and more energised during fast, but all I experienced was noticeable sluggishness (no glucose, only fat as energy source) and bit more pissy about small things (though I recognise it and never act on it).
P.S. Worth mentioning, any water fast above 4 days can be potentially dangerous if you don't take supplements that regulate your bodily functions, like salt, potassium, magnesium etc. I have read accounts of people doing only water fast no supplements for 10-15 days and report serious symptoms of their body shutting down (maily cells dying due to lack of salt).
Care must be taken to avoid potassium overdose if supplementing with potassium. Sodium chloride is well tolerated on the order of no more than 20 grams per day spread out over the whole day.
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Citation desperately needed.
With the obligatory 'In Mice' addendum.
For me, I try not to judge people for their body shape and listen to what they have to say regardless.
The "festooned set" is a common thing across YouTube influencers and affiliate marketers, this guy particularly likes to push bone broth and other keto related stuff. Doesn't mean he isn't damn well versed in the subject matter though.
If you like I can track down some old 3 hour long talks on autophagy and fasting if you'd prefer, those doc's are pretty funny too sometimes.
Also, I just pulled out a copy of the book I mentioned, and in the appendix he's got 467 citations. I'd say ballpark over half of those are peer reviewed medical journals.
Doesn't seem very duck-like, but I'm interested to hear your take on why he's a quack.
IME, there is always some nugget of truth behind bizarre public crazes.
But agree, fasting is great for cleaning up the biological cruft.