FYI The Hangover came out 12 years ago, Superbad came out 14 years ago. The rest of your post I'm not so interested in discussing, but comedy to me appears to be a genre that has moved to TV, like most genre fare for adults these days.
Those movies you mention weren't necessarily made to cater to foreign audiences, Hollywood may have always enjoyed making money from foreign audiences but the balance has largely shifted over the last several years to the point where foreign box offices and audiences come first and determine what films get made and their content, that's a big shift in my opinion.
So anything before the smartphone era is what... not-modern, sorta-modern?
If the founding of Uber (2009?) is a milestone of some sort, man I feel ancient.
Personally, I think I'd go with the release of the iPhone (June 2007).