The biggest change to working remote vs in-office is communication. Some organisations have done well and make sure communication is shared across all staff easily. Other organisations require proximity as you only get the full picture by overhearing random conversations. Over-hearing co-worker X is having a problem with tech Y in a different team that you used at your last employer is a great icebreaker. Knowing their area of knowledge may help you in the future with your taskings. Companies with distributed operations or that are remote only before the pandemic tend to do better, but some companies have actively transitioned and put those structures in place. Unfortunately many others have set up make do structures "until we can get back in the office".
As for helping or hurting your career, that is very dependent on your situation and the existing team structure and culture. You can overcome most negatives that come from working remote if the organisation supports you. You can also use the flexibility to improve productivity helping the organisation more. However there is more responsibility on you doing that, and some find themselves not mature enough to make the most of it.