I'm really looking forward to read this article, I've longed for an article about this for a long time. The problem becomes noticeable when for instance comparing colors on web apps with different screens. The colors can look different on the different screens, or if you use color profiles then the colors look different on apps that support it vs. apps that don't support it.

To my surprise the New Relic NRQL editor in light mode which heavily relies on highlighting for editing is hardly usable on my dated LCD screen which doesn't have a color profile I guess. (Safari supports color profiles actually) Luckily there's now the dark mode option...