Underlying Medical Conditions Among 540,667 Adults Hospitalized with Covid-19 | Hacker News Reader

Underlying Medical Conditions Among 540,667 Adults Hospitalized with Covid-19

cdc.gov

23 pointsnradov7 comments

> Anxiety and fear-related disorders were a prevalent condition in our sample; they were also the second highest risk factor for death among the underlying conditions considered in our study. The reasons for this finding are likely multifactorial and may include a reduced ability to prevent infection among patients with anxiety disorders, the immunomodulatory and/or cardiovascular effects of medications used to treat these disorders, or severe COVID-19 illness exacerbating anxiety disorders (19,20). In a subset of patients with pre-COVID encounters in our study, anxiety diagnosed before COVID-19 was not independently associated with death or IMV during COVID-19 hospitalization and, therefore, it is also plausible that anxiety was diagnosed during COVID-19 illness and may be a resulting sequela of COVID-19

No surprises about obesity, etc, but the connection with anxiety really stood out to me. I hope someone can follow up on this.

More and more, I'm finding its all about the homocysteine. It's correlated with all kinds of neurological problems with different names.

Something about it gets out of regulation by the body and the sufferer falls into the incident pit. Can be something as innocuous as antibiotics wrecking your digestion or a bad diet from being poor that begins the decline.

https://pubmed.ncbi.nlm.nih.gov/16102882/#:~:text=Homocystei....

Having severe Covid and being in mortal danger (or thinking you are) could make one somewhat anxious.

> Hypertension and disorders of lipid metabolism were the most frequent, whereas obesity, diabetes with complication, anxiety disorders, and the total number of conditions

Everyone probably could have guessed this result (doesn’t mean this is bad science!).

I wonder if this distribution is similar for all other (non-covid-related) hospitalizations too.

Yes another study reached similar conclusions over a year ago. It's good to have the results reproduced with a larger study.

https://feinstein.northwell.edu/news/the-latest/largest-covi...

This is my first post on hackernews, I registered as I feel this perspective isn’t but should be considered: Many had already came to this conclusion based on available data around the middle of 2020; however, the body of this report (that the virus mainly harms already-unhealthy individuals, not the majority of the population) as well as the corollary (widespread lockdowns are not required/will statistically do more harm than good as only at-risk individuals should self-isolate) were universally regarded as a “wild, baseless, unhinged, and potentially sinophobic conspiracy theory” by most social media, “fact” “checkers”, and large news organizations; sharing this CDC report’s sentiment would result in the individual sharing it experiencing “de-boosting” and “‘platform integrity’ moderation activity” (hidden post and banning). Is it the case that earlier insistence of “the science is settled” and the corresponding moderation activity was too confident? Major news organizations were stating as solid facts their position on COVID-19’s origins, as well as information surrounding it, but are now walking back those claims - should we reevaluate our confidence ratings we assign to news agencies’ outputs, or was this a special case? If so, why?

I find it odd that cancer wasn't sufficiently prevalent in the hospitalized population to make the 10% threshold for inclusion.

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