A library[1] small molecule drug that reverses dementia by acting on a calcium channel based on mouse data?
Press X to Doubt
Press X to Doubt
If you evaluate the mechanism they explain, your prognosis will be better informed. Really the size of the molecule is neither here nor there. It's the therapeutic application that counts.
> SAK3 enhanced the proteasome activity via CaMKII activation
Consider why that might be effective.
It is explained clearly in their AD paper abstract.