Quite a bit less effective and why the WHO is saying fully vaccinated should still mask up inside.
Edit to add: 70% effective vs. 95%+ is a significant reduction.
Edit to add: 70% effective vs. 95%+ is a significant reduction.
If you're talking Alpha vs Delta and about hospitalisation/death, then the vaccines are actually marginally more effective against Delta than Alpha according to data from Public Health England (although there's significant overlap in the confidence intervals).