What about the new Delta variant?
should we see a variant that escapes this RBD Antibody mechanism then there will be a possibility of escape, and concommitant requirement to tweak the vaccine antigen.
Edit to add: 70% effective vs. 95%+ is a significant reduction.
If you're talking Alpha vs Delta and about hospitalisation/death, then the vaccines are actually marginally more effective against Delta than Alpha according to data from Public Health England (although there's significant overlap in the confidence intervals).