* Use the Reddit Enhancement Suite browser extension, and customize to your liking.
* Set it to permanent old.reddit.com mode, so all reddit links immediately go there.
* Only browse reddit on mobile using one of several third-party apps, like Relay (my preference), Boost, or Apollo.
* Extensively tailor your subreddit selection to weed out the garbage. Most if not all of the default subreddits are terrible, but anything devoted to a niche interest is likely to be a welcoming and respectful community.
I don't have avatars, autoplay videos, or inline "promoted" threads. I see 10 levels of nested comments with 1000 comments loaded by default. Additional levels of nesting are tap to open. I have keyboard navigation on desktop and swipe navigation (from link to comments back to home page) on mobile.
Pretty much all of the complaints that folks have in here are solved problems.