I recently switched to PipeWire on NixOS 21.05 release. It was mostly seamless (except for some issues of not running it at realtime with rtkit, something that PulseAudio does automatically) and having access to new codecs like mSBC and SBC-XQ for Bluetooth is great.

It is very early though and lacks documentation like the article posted above says. Wouldn't recommend for everyone yet, but sure it is nice to see almost no issues in a project that is still on its early stages.